I have bad road noise after 40 mph. This started after changed tires and both front boots and axles

Drive shaft!

Did you recently change your tires? An aggresive tread design, like a mud and snow tread, can create road noise that becomes more noticable at higher speeds. Bad wheel bearings can also produce a "roaring" sound, especially in front wheel drive cars. To check them, jack the front wheel up and spin the tire by hand. It won't spin smoth and even, there will be some resistance and you will hear grinding or crunching.

If your transmission was low enough on fluid, it could conceivably make noise. Also check your U joints or CV joints for play. any play in them will make noise although it is usually accompanied by a feeling of looseness or "jerking", especially when making changes in direction or speed.

There can be a lot of reasons for noise, but start by checking these things first. Hope this helps.

This is your one of your axels.. they are damaged inside.. Get them removed asap it can cause major damage if it brakes loose..each axle costs about $90-100

caster,camber and, wheel bearings
have your car 4 wheel aligned this will adjust your rear caster and, camber.
have your wheel bearings checked

the tires make steady noise , check the wheel bearing as noises get high and low at the same speed , and i also would check for diff if it's 4wd.

The one thing you did not mention that I needed to do to remove the Hum was 4 wheel alignment. Smooth and quiet now. Hope that helps and have a great day.

Check the right side engine mount ASAP!
Call the dealer and give them the VIN number.

There is a new TOYOTA part no. 123052-0D120 to address this problem.

The old design on 05 and 06 has the noise problem.

In order to pin point the problem I will need the VIN number.

Please post it and I will follow up on it.

Tire/wheel balance or front end alignment problem

drive shaft universals worn.check rubber boots ok with no splits or or leaking grease.If boots have split and dirt got in then change the ends only,but its possible to remove the end and by turning cage around extract the ball bearings,wash the lot out with diesel and fit a new boot and re pack with grease ---yes i know it could still knock a bit and fitting new yea yea but it might work and evan if their is a bit of noise on turn ignore it till it gets really bad as they could last another 100,000 kms

whoa! You have what sounds like a serious front end problem. Jack up the car, use safety stands to support it, block the rear wheels front and back. Look behind the left front wheel, look at the axle boot . Do you see any rips, splits, or grease ? The boot may have torn, letting in road debris which will destroy the axle, causing it to make a rattle or rubbing noise when you turn.. If the boot looks ok all around, grab hold of the tire one hand on the top, one on the bottom, push and pull the tire in opposite directions (top in, bottom out, top in bottom out) and have some one look under the car in the area behind the wheel to see if anything is moving around. Do the same w/ one hand on front of tire (9 oclock position) and back of tire (3 oclock position), and again try to force the wheel in and out, while someone looks underneath for any component that moves around. If the front end is ok, you won't see any movement. You may have a badly worn tie rod or ball joint, this could also cause the car to wander on the highway. Check it asap, as the next step is for something to 'let go' and you can lose control of the car. Let me know what u find. good luck countrycurt0