Yes it can. There is a thick WHITE colored wire, that needs to power up as a true ignition wire or it will not activate the electrical portion of your transmission. This is a common known problem especially with dealing with remote starters in these vehicles.
What's my problem 2008 duramax GMC it gets stock 4 gear and I change my transmission my module and wire harness
I have a chevy expr er van .can a bad ignition cause problems with transmission
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