2006 lexus Rx 330, rear hatch button and handle will not open or close door, key fob does not work or button on dashboard to open hatch. Interestingly I opened the door, it went all the way up and then would not close until we disassembled the motor. Is this a motor issue, computer issue or some other reason? thanks

(1) How to fix automatic power liftgate that is not working on a Lexus RX - YouTube

In link below it was said he manually had to close by pulling down and then up a little and then down and the back up a little. The hatch was eventually closed, and it reset(read it in below link.
Lexus RX 350 Questions - The hatchback door will not close using the button on the door and it ... - CarGurus

(1) 5 SECRETS About The Lexus RX 350 Power Rear Door - YouTube

Back door - Opening, closing and locking the doors - Before driving - Lexus RX 450H User Manual - Lexus RX - Lexus manuals (lexomans.com)

chk fuse,or release silanode

Visit an on-line parts supplier and purchase a new switch/touchpad for inside of the rear handle. Local parts supplier probably won't have it. You can replace it yourself. I did when I owned one of these part pits.

the battery is dead

Use the manual release inside the trunk, it is tiny cable with a plastic handle on it.

https://www.clublexus.com/forums/rx-1st-gen-1999-2003/395765-driver-door-won-t-lock-or-unlock-using-key-transmitter.html

Sounds like either the hatch is not closed completely or the switch is says the door is still open. verify if the door is shut tight.

Did you check the button that you can accidently switch on the inside of the glove box? It controls the motor that opens the power back door.

Inside the glove box on the left side there is an on/off switch, which m,ay have been bumped off thereby shutting off the power controls to the hatch. Check that first. Then press the unlock button on your key twice, then test all 3 power hatch buttons to test them, one each on lower left dash by the gas cap door release, one on fob and the one at the hatch. If they still do not work it is possible your door may need to be 'initialized" by your dealer due to power failure. I have seen this with seats and windows but never with the rear door....

the switch to detect hatch close is not being pressed down ..check at the striker there is a switch there confirm it is is working by pressing down on it with your finger and watching the light on the instrument panel