Yes you can,
dont forget to install its driver first.
Assuming the drivers and other software are installed, you would open the MP Navigator application, then launch one of the following, depending on what you want to scan:
Easy PhotoPrint
Presto! PageManager
Scansoft OmniPage SE
Reference: page 91 of the User's Guide.
Have you tried the Mac OS X software/driver available on their website?
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