1000 yd range, savage, 30 in. bbl, 8-1 twist, what bullet n powder would you use

The twist of a Savage Axis factory barrel chambered in 6.5 Creedmoor is 1:8

Make sure you know your terminology.
The bullet is what comes out of the business end of the barrel.
There is no powder in the bullet (guessing you are not using a tracer bullet which does have chemicals in it to make it glow.)
The firing pin is in the bolt of the rifle and not part of the bullet.
The case is what holds the powder and the bullet. The primer in the end of the case is what the firing pin strikes in order to ignite the powder and fire the bullet.
You can drill a hole anywhere in a bullet (as defined above) and not have any problems.

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Your Savage 99 was mfg. in 1903.

Even in my reloading book if you load over max with an H4350 on a 85 gr. bullet you only get 3235. If you drop to a 70 gr. bullet you can get 3457.

No, this is not a scope issue. The scope is raised above the centerline of the barrel, thus at 10 yards, the barrell is actually slightly raised in relation to the centerline of the scope in order to hit your point of aim. Since the front of the barrel is slightly inclined, at 25 yards the bullet is still rising in relation to the scope alignment. Backing up to 50 yards you will begin to see the bullet start to drop back down, at 100 yards it may drop as much as 8-10 inches, and at 200 yards, it may drop as much as 52 inches. This is assuming that you are shooting a standard velocity .22 long rifle cartridge (1050 feet per second or so).