When I plug in my Targus hard shell keyboard to be changed do the red light is suppose to be on

faulty power adapter port, may have blue light meaning charger is working normally, double check with another working power adapter or use your adapter with another keyboard to check which device has problem, power adapter or keyboard port.

Thank you!!! I held the home key and power button until the Apple logo appeared and now it connects to the key pad.

click start control panel administration tool computer managenent device manager scroll to mice and other pointing devices you might see a yellow question mark? right click to update drivers
make sure the lead from the mouse has a secure seating and the lead is not bad/faulty
(if applicable)
make sure the battery is good (has full charge)also you might test the usb device for the mouse is inserted correctly into the usb port (if applicable)
click start control panel mouse you should see 4 tabs buttons,pointers,pointer options and hardware under hardware you can troubleshoot also you can select properties under driver you will have options to update driver,rollback driver or uninstall and under hardware you can troubleshoot
in xp
hope this helps dont forget to vote

There are buttons on the transmitter/receiver and the mouse(small red on bottom). Turn off the mouse. Plug in the USB Tx/Rx and hold down the button. Then press the red button on the mouse and hold for one second. Do this until the rapidly flashing light on the Tx/Rx slows down. The unit's frequencies are then encoded/decode and can communicate.

have you tried to change batteries? low battery will cause your mouse not to connect to the receiver.

my samsung laptop is green when charged, red when charging.
try turning it on with the power adaptor plugged in and the battery removed.
if this works, i assume your battery is damaged

Try pressing both the red syncing button and the black reset button (on the base of the USB-connected charger( simultaneously.

I would check the power adapter with a voltage meter. It sounds like the adapter might be defective. The wire at the end of my adapter broke after a month or so of use. I picked up a targus replacement. The only problem since then is the targus plug is a bit loose.
Best wishes

SOUNDS LIKE A BAD MOUSE, AND WHEN YOU GET THE NEW ONE DO NOT OVER CHARGE. I.E NO CHARGING OVER NIGHT THE DIRECTIONS WILL SAY SOMETHING LIKE CHARGE FOR 4-6 HOURS NEVER DO OVERNIGHT CHARGING WITH ANY ELECTRONICS

If the Red Light is on the batteries should be good enough to function. Try
Normal 0 Turn the mouse over and find the small rest/connect button on the bottom of the mouse and press it. This should connect the mouse to the receiver and work properly. If not, try pressing the receiver button and then press the button on the mouse. This should be done whenever you change batteries or glitch.
Hope this helps you. Bud