My dell inspirion 5160 when I turn power on just comes to F2 and F12 and then goes to blank screen. Ifi punch F2 or F12 it just beeps and the screen stays blank.

F2 usually takes you to the BIOS setup screen, you need to hit the keys as soon as you power up.

F12 selects on a Dell instant boot menu to select booting from CD-ROM, USB, etc rather than the BIOS options.

F8 goes to safe mode start up for windows, this must be done before the windows logo comes up (ie when it is a black screen).

Control - Alt -Delete Keys together can be used any time, after windows boots as it tells it to re-boot the computer, back to start up.

do wut it tells u, check cable

You are asking for trouble by placing programs that Windows uses on the other drive. You are better off using the 1 TB drive as a system drive. Sounds like your OS is corrupted.

Motherboard is toast!

Your hard drive is shot. It's time to either put in a new one, or take it to a repair shop.

Turn off vista hybrid sleep and hibernation mode. It causes more problems then it helps.

Hold down the power button for about 10 seconds untill it powers down and restart entering the correct password..

the easiest solution would be to re-install windows and hope it is not a hardware problem

well, then, lend me your ears, eh?

sounds like you're right on the front door of a possible motherboard major headache, with charging and usb ports unhappy.

this still under warranty? Check here to make sure

you might have deleted/corrupted some of your boot files so you might want to restore your default to be able to retrieve your old booth. then try fixing it from there.