Is there any spray out there that will calm my cat down

Hello Patricia...
If you mentioned the exact reason for which you are looking for spray then it's quite easy to answer this question. As nowadays most of the cat owners have the question "how to stop cat from peeing on carpet" If you also have the same problem then you should have to consult veterinary and do the checkup.
As you are looking for sprays to calm down your cat then I would suggest you take Nature's Miracle spray. It's especially for cats to keep calm down.

Kevin- there are several sprays made for this. Feliway makes a spray, plug in diffuser, and a collar. The Feliway formula is made to mimic the facial pheromones of cats so it is calming for them. I use it for my cattery and for the quarantine area. There is also a liquid by Bach 'Rescue Remedy' it is tasteless and can be added to food or drinking water as well as directly administered via a small dropper. Have had much success with both for my show babies

Are you taking your cat for rides in the car? Why should it be a spray and not a pill or medicine? Do you keep the cat in a carrier while it is riding? Is the cat normally calm? It depends. I think there are tranquilizers that work on cats similarly to how they work on us, but of course the dose is different, and the neurological system of a cat has some big differences. I think they are taken in a pill not a spray, unless you want to tranquilize yourself at the same time. I wondered if the pet is fixed (spayed or neutered) because cats that aren't have more wild-acting tendencies.