If you check the Creative forums there is a thread there where a few people have started to fix problems like this permanently and they have helped quite a few people fix their problems. I would only suggest checking it out if you have any electronics experience (soldering, and basic troubleshooting minimum). Otherwise I would send it back but keep in mind that this is one of a few common problems with the S750's and you are likely to have other problems in the future unless you take measures to fix the problem that creative has not.
I would also like to point out that your problem would be a short on one of the amp boards after the power regulators, very likely one of the STA575 amplifier ICs. Those are not easy to find but it is possible to find replacements.
There isn't much you can do I'm afraid. If you were still in warranty Creative would replace the sub.. but as I found 2 months out of warranty, they really didn't want to know. Their solution was buy a brand new system. This problem of the subs "blowing up" can happen from the moment you first turn it on to a few years down the line. My system had never been over half volume, and was well looked after. Such a nice product, sound is great! BUT, with the risk of it blowing up at any moment... I just cant find it in my heart to blow another £300 on one. Creative do not recognise there is a fault with the system, even though hundreds or even thousands of people have the same problem. Their customer support really sucks!! I love creative products, but I cant see me buying any more of them. They are a giant let down. Awesome product while it lasts, **** service, **** internal components, **** support, **** company. A real shame.
This is obviously an OLD thread and an equally old device. However, I just started experiencing this problem. My sub will not power on and the green Power light just randomly pulsates. I opened it up and started heating it as was suggested on some other boards. When this didn't seem to work I conducted a visual inspection and found what is in the attached photo. I don't know my capacitor from my resistor so I'm not sure what these parts are that have gone bad but the blue part and the adjacent brown part have seen better days. I don't know electronic components but I have built two 3D printer kits so I can follow technical instructions and improvise when needed. Are these very easy to replace? Has anyone resorted to replacing any of the electronics in their S750? Where did you source the parts? I would love to be able to save my system from becoming e-waste. Thank you to anyone who can help. 
The Amplifier or its power pack has failed. I would not know of a repair possibility[No user serviceable parts in side] is usually stuck some where on the units like this because they are integrated boards and service is by replacement. If it is of recent purchase get onto whomsoever you got it from.
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I have a similar problem although my speakers are soldiering on with drastically reduced power. I switched on the unit using the rocker switch on the rear of the subwoofer unit. A loud crack came from inside followed by a white flash of light and that unmistakable smell of electronics that have fried. :( I unscrewed the back plate to see the damage which turned out to be a component on the power board, there was a black burn mark on the green board. I was shocked to see how messy and shoddy everything was on the PCBs. Obvious signs of hurried careless work - made me sad to see it. No wonder there are so many problems with this system. I have had two breakdowns. Waited four months for the first repair in Singapore at Creative HQ. I complained but they could not care less. The founder of Creative is a Singapore native and something of a local hero. It's a pity he gets all the manufacturing done in China on the cheap.
Same problem here, mine out of warranty so no support from creative what so ever.
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