Unsupported cartridge both ink cartridges applied and printer will not work with comment "unsupported cartridge"

(1) Open the printer and wait for the carriage to slide over. If for some reason it does not follow these instructions:
(a) Unplug the printer
(b) Manually slide the carriage over until you can get the ink cartridges out.
(2) Remove the ink cartridges from the print head.
(3) Use cotton swabs dipped in hot water or a mix of hot water and isopropyl alcohol to thoroughly clean the print head.
(4) Repeat this until there is no ink residue coming off on the cotton swab.
(5) Once finished, allow to dry and replace the cartridges
(6) Try to print something now

If that does not work then you have one of two possibilities:
(1) One of the ink cartridges is defective and causing the error
(2) If it's definitely not that, then the print head will need to be replaced.

Hope It's resolve all Your Printer Problem,
Or Still having Problem Then follow Us For Canon Printer Support

Had the same issue, bought some cheap inks off the internet and the printer wouldn't accept them, bought the proper dell cartridge did a head clean and it worked ok.

Though Lexmark does not recommend using refilled ink cartridges, you may try to refer to this article in the Lexmark website on Unsupported Cartridge Error on a Lexmark X3330/X3350 All-In-One to determine and resolve the problem. If error continues, try to insert a different known working cartridge. Thanks.

that can be happened with some problem of cartridge or cartridge holder.
if you can check the printer with your older empty cartridge, and you can see
the different error message with that , it says your printer is OK.
and have some problem with your cartridge.and need to replace it.

if you can see same message with your old and empty cartridge,
you can clean both of cartridge the connecting pads ( in printer cartridge holder and
back side of the cartridge ) using by IPA and check again.
if had corrosion or some ink swallowed problem , can be clean with that.

after that if you got same result, you need to check your cartridge with
another printer or your printer with another good cartridge.

Problem Unsupported Cartridge; Error: "Unsupported cartridge"; Incompatible cartridge error; Incompatible cartridge in the printer; Cartridge not recognized Solution What you will see
When a cartridge is inserted, an Unsupported Cartridge error message is displayed on the printer operator panel.
Affected printers
This issue affects printers sold exclusively in the Dixon Store Group (DSG) in Europe and in Circuit City in the U.S. NOTE: The cartridges for these printers are sold exclusively in these stores or on their websites.
Explanation
The printers listed in the table below are compatible with a #2 cartridge (in single cartridge printers) or a combination of #2 and #3 cartridges (in two-cartridge printers). They do not support the standard color 28A 35, and Mono 29A 34 ink cartridges. If the standard color 28A 35 or Mono 29A 34 ink cartridges are used in these printers, they will fail to print and the printer will post an Unsupported Cartridge error message.
Solution
Lexmark recommends using either a #2 cartridge for single-cartridge printers or a combination of #2 and #3 cartridges in two-cartridge printers.

Cartridge compatibility chart

NOTE: These printers are sold exclusively in the Dixon Store Group (DSG) in Europe and in Circuit City in the U.S. The cartridges for these printers are sold exclusively in these stores or on their websites.
Item Printer #2 Color Cartridge #3 Mono Cartridge #31 Photo Cartridge 1 Lexmark Z738 Yes ... ... 2 Lexmark Z1380 Yes Yes Yes 3 Lexmark Z1480 Yes Yes ... 4 Lexmark X2480 Yes ... ... 5 Lexmark X2580 Yes Yes Yes 6 Lexmark X3480 Yes ... ... 7 Lexmark X3580 Yes Yes Yes 8 Lexmark X4580 Yes Yes Yes

If it is not a Dell ink cartridge, it won't work. Dell has it to where you have to buy their cartridge.

I was having this problem with a Z730. The printer was finally working again after removing and inserting ink cartridge like 40-50 times. No pun intended. After installing cartridge try turning off printer and then back on.

Try replacing the cartridge with a new Dell ink cartridge, the refill may have gone bad.

Unload and reload the Lexmark software........AND clean the printer contacts,
not neccessarily the cartridge contacts.........
that outta do it.