I have a 1965 ford mustang v6, it has a very tough start and the engine shakes. in order to drive it I had to keep the throttle compressed and in a short distance it begins to smoke and shuts down.

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Check your drive line for any dents or missing weights

more detail, please. Does it shake at idle in neutral? If yes, not likely transmission.
Does it shake while sitting still? Only while driving? If while moving, check wheels/tires/brakes.

you need to find the tdc on compression cylinder number one and poin dist rotor to face cylinder one on the cap

Not exactly. The Mustang of that series had leaf springs and "overload" springs were usually a set with an extra leaf or two. Overload shocks were shock absorbers with an additional coil spring.
I don't think you could special order overload springs since the car was not designed to haul any extra weight like a truck or station wagon.

It sounds like he has the spark plug wires in the wrong firing order. Those are the "hoses" you see on the distributor cap. He changed the rotor $7 part. The timing won't make it shake. It can be off 10 degrees from specification an still run ok. Is it a 6 cylinder or V8?

I'm pretty sure he has 2 spark plug wires out of order. He needs to look up firing order of engine.
When he transferred wires from the distributor cap or put them back on after the plug change, he must have put 2 in different places.

Only other possibility is he cracked a spark plug installing them, it happens.

Try this. If the distributor is in the right way, the clips that hold the cap on should be just a hair off of 12 o'clock and 6 o'clock. #1 is positioned at 1 o'clock, which is at the firewall side of the distributor. The firing order is 1-5-4-2-6-3-7-8and is counterclockwise from #1. The passenger's side is cylinders 1-2-3-4, from the front of the car. The driver's side is 5-6-7-8 from the front. Hope this will help.

I presume you mean the correct adjustment.... My preference is to have the shift points come a little late...

the correct adjustment is somewhat subjective, but when driving along, easy throttle, and come to a slight incline, the trans needs to shift down at some point, adjust until it does. Not enough means you really have to press the throttle, too much means the shift happens too early...

It is forgiving within those parameters...

sound like your UPPER control arm bushings are worn out.....they can be lubed with a aftermarket kit installed to the zerk fittings.....GL

check for fuel, spark and compression. these are the only things needed for a engine to run