Trouble code P0043 means: HO2S Heater Control Circuit Low (Bank 1, Sensor 3)Hex code 43 is for a misfire.
DTC 43 indicates a cylinder misfire, but does not specify which cylinder is misfiring. To pinpoint which cylinder is misfiring, you need a scan tool and get the "P" code, as you can see in the chart below. So it is quite possible you're barking up the wrong tree.
If you go to an Autozone they will scan the codes for you, if the CEL is currently on, and tell you the DTCs they find. That will get you closer to the problem.
I'm fairly confident that if you do a complete tune-up, spark plugs, spark plug wires, distributor cap and rotor, that the misfire codes will be taken care of. Be sure you read this,
Dodge Ram 1500 Running Rough before replacing the spark plug wires, or if you have already replaced them.
Hope this help (remember comment and rated this)..
what engine ???
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