X type jag 3.0 V6 petrol, engine management light illumunated, doesn't sound right on intake, all codes relate to engine misfires, changed plugs, coil packs, compressions ok, no air leaks on or around manifold, fitted new timing chains and tensioners also noticed fuel pressure drop on live data only for split second when fault occurs so fitted new fuel pump still no different, codes showing at moment p0300 random/multiple misfires and p1313 coil pack no2 but sometimes changes to p0300 random/multiple misfires and misfires on 1,3,5?

Hi, What causes a cylinder to misfire? Basically, it's one of three things: loss of spark; the air/fuel mixture is too far out of balance to ignite; or loss of compression. Loss of spark includes anything that prevents coil voltage from jumping the electrode gap at the end of the spark plug. Causes include worn, fouled or damaged spark plugs, bad spark plug wires or even a cracked distributor cap. A weak coil or excessive rotor gas inside a distributor would affect all cylinders, not just a single cylinder.

If you find a P0300 random misfire code, it means the misfire is random and is moving around from cylinder to cylinder. The cause here would likely be something that upsets the engine's air/fuel mixture, such as a major vacuum leak, a leaky EGR valve or unusually low fuel pressure (weak pump or faulty pressure regulator).

In the case of a steady misfire, isolating the misfiring cylinder is the first step in diagnosing the problem. The old-fashioned method for finding a weak cylinder is to temporarily disconnect each of the spark plug wires, one at a time, while the engine is idling. When there's no change in the idle speed, then you have pinpointed the weak cylinder.
A power balance test will tell you the same thing, but this requires some hookups and an engine analyzer. A power balance test is preferable to pulling plug wires, because it keeps you away from the voltage and prevents the voltage from causing any damage to the electronics in the ignition system.
When a plug wire is physically disconnected from a spark plug, the high voltage surge from the coil cannot follow its normal path to ground through the plug wire and spark plug, so it passes back through the coil. Most ignition systems are robust enough to withstand such voltage backups intermittently but not on a prolonged basis. If the coil or ignition module is already weak, it may push the component over the brink causing it to fail.