When do spark plugs need to be changed on a 2007 toyota 4 runner?

This site and video will help you find the cylinder you are looking for and how to change your plugs.
Fig. 5VZ-FE engine Firing order: 123456Dis
https://www.autozone.com/repairguides/Toyota-Pick-ups-Land-Cruiser-and-4-Runner-1997-00/FIRING-ORDERS/FIRING-ORDERS/_/P-0900c152802618eb

https://www.youtube.com/watch?v=VDBdp8rjYkw

I am confused. Does it have a distributor cap, rotor and spark plug wires, or does it have coil packs sitting on top of spark plugs?

Is there spark and fuel flow to the engine?

1-4
2-5
3-6

bring it to a garage

at 50,000 miles there is really no need. i would wait and save up that money and do a transmission flush 7- 10 quarts of toyota f-type fluid can be costly but a flush removes all of the fluid and garnish along with any fine shavings (normal wear and tear) out of the tranny and replaces it with new clean fluid. normal intervals would be at about 80-100,000 miles. you should be able to find preventative maintenance schedules in your owners manual. if not any repair facility would have it on their computer.

check www.4x4wire.com i was just there looking for the same thing and found step by step directions on how to do it

Follow the plug wires to the location of the plugs. You will need swivel scokets or sometime called wobble sockets to get to where there located and long extentions, plus a lot of time!!!!

They are under the plenum. Hard to get to unless you remove the plenum.

contact your local Autozone parts store and they can give you a print out for free.