Key will not physically unlock door only with remote it will unlock why wont key unlock driver door?

A plastic clip that holds the lock linkage is probably broke or worn. You need to pull of the inner door panel to see whats going on inside. Use the remote and see whats happening. It could be bent rod in door from someone using a slim jim to unlock it when they locked the keys in it at some point. Bend the rod and try the remote again untill it works properly.

Check your owner manual and go to the unlock section, you may be able to change the settings of your choice.

Could be a few things. Do they unlock from the central locking switch in the car? Close all the doors first then push the button. Do they unlock with the key remote? Does the drivers door unlock when the key is inserted? If they don't work at all check the fuse in the trunk area on the right side. There is a panel that pulls down and reveals 5-10 fuses.

Year make and model. You may have a inoperative door lock actuator.

change battery in remote

The remote likely needs to be reprogramed. If you have both remotes you will need to take these to the dealer and have them reprogramed.

Sounds to me like perhaps there's an electrical issue going on here. You will probably need to take it to a mechanic or dealer to get fixed. I mean, if both the remote and the buttons fail to lock/unlock, it really sounds like an electrical issue.
Do any of the buttons work on any of the doors? If so, it may just be the driver's door that has a problem.

Check the remote battery or replace. Check all fuses. If you need to reprogram, try this.

key not in ignition.
driver door open-others closed
driver door unlocked

1-insert and remove key from ignition two times

2-close and open driver door two times

3-insert and remove key once from ign.

4-close and open drvr door twice

5-insert key into ign.,then close driver door

6-turn key to on (not start) then off, twice
this is rewrite mode,have all remotes to reprogram
it will clear any lost remotes.

7-remove key from ignition,the door locks should cycle twice.if not start over.it may take a few tries.

8-press lock/unlock together and hold for a second

9-release,and press lock on remote,the door locks will cycle confirming program.continue to do other remotes you have,steps 8 and 9.if only one in possesion,you are done.

to end mode open door or insert key into ig.you can do up to 4 remotes.read this a couple of times to get the sequence down.there are time restraints,but if you go in order it will work.do not wait more than a second b/t each step and you will be ok.i know from experience that you can do this as fast as you can and it will enter mode.if steps out of order or you wait to long it wont.print this and have in lap,read ahead of what you are doing.good luck

Either the wring going to that motor or the motor itself is bad.

can you use the key its self on the rear door. what i mean is not using the remote but actually using the key?