2003 Pontiac Aztec 3.4L V6 misfire in cylinder 2- PO302 The vehicle had a major tuneup including ignition coils. We replaced the fuel injector on cylinder two and it did not help.

SOURCE: cylinder 3 misfire

Make sure you're using the recommended spark plugs. When my car did that, I had put Bosch Platinum Plus-4 plugs in and got that same problem. Turns out the plugs are too hot and cause it to fire prematurely and kick the misfire code.

SOURCE: Pontiac Grand Am 97'

there are no wires on the 2000, they are coil packs. i have the same problem with mine, cylinders 2 and 3 misfiring. i took it to a local repair shop and replaced the ICM and the coil packs and it is still doing it. any ideas would be greatly appreciated i dont want to keep replacing parts i dont need to

SOURCE: engine misfire

we have the same problem down to the lights and everything
Did you ever figure out what it was?

SOURCE: I have a 1996 Pontiac Grand AM GT 2.4 L. I got a

fuel injector sound like the problem if you have checked the power with a node test the injector and you have pwer then mest likely the ijector is clogged ,so first make shure you have power to the injector hope this is helpfull

SOURCE: 1999 Grand Am 3400 v6 misfire.

I was asking about the pushrods because I had this problem with one of these engines that had a bent push-rod. I robbed a push-rod out of an older 3100 and it was just a fraction of an inch longer which bottomed out the lifter. I figured it out by removing the valve cover and loosing the rockers when it was running and it smoothed out. I'm guessing you checked for vacuum leaks already. How about injection pulse on the number 6 cylinder when running. Another thing you could check is running compression. You said you checked compression but did you just check cranking compression or did you check running compression too.