Well, a simple google search (looked for "2002 dodge durango codes p0601") led me to this web site:
http://www.obd-codes.com/p0601 which says it is a problem with your PCM (Powertrain Control Module).
Things that can kill a vehicle's computer are things like using a welder on the car. If you disconnect the wires/connector from the PCM while the battery is still connected, that may also cause this code. But, it most cases it means your PCM has gone bad, and you will probably have to have it replaced.
Try resetting the code first (O'reilly's will do that for free), and see if it comes back. If not, it might have just been a glitch. If it comes back constantly, then your PCM may be shot.
Although your car may work even with this code, you may not be getting the best gas mileage or performance if the PCM is not working correrctly.
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