On 2005 Buick LaCrosse Cx do I have to remove the wheel to take off original hubcap?

try this link:
https://www.justanswer.com/buick/8ybux-buick-lacrosse-cx-remove-lock-cylinder.html

in the fuel tank.
Fuel pump replacement Buick LaCrosse 2005 2013 Gas 3 0 V6

Its behind the vibration dampener and crank pulley.

Sampson, sounds like a bunt out bulb, which will need changed.
If you feel comfortable doing it yourself. Basically three screws, and you have to pull one plastic fastener from the fascia (bumper) and pull the bumper back a bit, and pull the assembly out. I believe it is in the manual, not bad to do. I will post a link to tell or show you how to do it. Press the helpful button

Headlight Change 2005 2009 Buick LaCrosse 2006 Buick LaCrosse CX 3 8L V6

2008 Buick LaCrosse Headlight Replacement

Thread how do replace the headlight bulb in 2005 buick lacrosse

Headlight Bulbs

I tried to upload a photo but the site wont let me

Here is a link that will show you how to
Tail Light Change 2005 2009 Buick LaCrosse 2006 Buick LaCrosse CX 3 8L V6

follow this link as has video of the procedure which is simple but easier to send video than to type the procedure
Battery Replacement 2010 2013 Buick LaCrosse 2011 Buick LaCrosse CX 2...

an alignment shop , cant do it at home

disconnect battery with key off ! and set for 10 min. then rehook up battery and check radio, might take care of it !

The relay under the hood may have gone out. We had the same problem on our 2007 Buick LaCrosse CX. The bulbs were fine, high beams worked, all turn signals and everything except the low beams turned on. Turns out the relay had gone bad.