I have a 2004 lexus es330, cranks no start. i have fuel on the rail..no spark at plugs. replaced both cam sensors,crank sensor . checked belt and cam timing. still no fire at plugs??? any ideas??

Did u check the timing belt. Does it crank over faster than normal?

When you say tou have fuel i assume there is fuel at the rail you need to make sure your injectors are spraying , one way is to disconect the coils so no spark remove the fuel rail with injectors and crank if there is no fuel there's the reason for no start . If this is the case check fuel pressure and check the injector wires for the pulse to fire

If you're getting a crank code, then change the crank position sensor.....

check that the cam shaft is turning ( broken timing belt/chain will not allow position sensors to give spark). Check that the immobiliser is operational. have the fault codes read

No spark? Then there is probably no signal to trigger the spark. Possible causes:
1) Cam position sensor.
2) Crank position sensor (you replaced it)
3) Coils (already replaced)
3) Wiring and connections to and from coils (bad grounding points or bad live feeds)

Suggestion: Stop the guessing and spending with "probable" causes. Have the car scannned for error codes and start from scratch according to error codes.

In a 96 Jeep not many sensors are involved. Basically Fuel and spark delivery at right time should start car if your Starter is able to crank the Engine.
If engine is cranking then the battery is Okay. Check Spark directly at the spark plugs and fuel pressure at the fuel rail. You may pull out one spark plug and check spark out of engine.
Try spraying Starting fluid in Air Intake while cranking. If Jeep starts then not enough fuel is being delivered by fuel pump. If you find no spark at plugs then check circuit for starter relay, Crank sensor/cam sensor problems.
A kill switch or bad Alarm system can also cause this problem.
Here is the Elec Diagram:
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I’m happy to assist further over the phone at https://www.6ya.com/expert/uttamjeet_2f3adc18600f8ede

Crank sensor is primarily for the spark and the cam sensor is for fuel management, crank/cam correlation for misfire purposes I would also change the wires.

Well at its most basic level, any internal combustion engine needs 3 things to run, air, fuel and ignition. You know you have fuel, so that leaves air and ignition. Check for spark first, then check your mass airflow sensor, if thats bad, that could be your problem.

could very well be a faulty sensor, leaky vaccum hose, bad coil packs, needing of new fuel filter, spark plugs, wires.

Have you checked your fuel pressure to make sure it is good. You can do this with fuel pressure tester on the fuel rail.

Also check every cylinder for spark
If you don't have any spark, or very weak spark, you could have bad coil pack, module, or crank sensor.

You can remove one plug at a time, and place it back on plug wire, place it on top of engine block, have someone else turn motor over well you observe to see if there is spark.

Do you have a service or check engine light on? If so, I would have the engine codes read to pinpoint exact problem area.

Let me know if you have any questions or need further help

ok, i tell you 3 possible causes.
check maf sensor connection , check fuel pressure regulator (max press fuel in rail 40 psi) , check engine compression (min 95 psi ) if less this cause spark plugs wet and not start