Replaced a spark plug wire that was arcing to fix an unrelated problem and the car drove fine until you put it under heavy acceleration. It would backfire and lose all power until u let off the gas. A mechanic told me to change my tps so i did and now my camaro won't start. I've taken it off 6 times and reclocked, cleaned the iac and checked vacuum lines. I reset te computer and it ran for 5 minutes and shut off and wouldn't start back up. 1995 camaro 3.4l 5speed. Help please!

Year make and model. Is the security light staying on/flashing? Pull a spark plug wire and see if it has spark. That could be a coil/s or crank sensor.

Re-Check the wires. One may have come loose. For external coils, check there first. Next, make sure that the rotor is properly seated inside the cap on the Distributor.
Did you also replace any of the spark plugs?
It could also be completely unrelated. Haha. Check for fuel pump operations, and that you are getting fuel. Its either air/fuel/spark.
But definitely check the wires and rotor. Hopefully you put the securing screw back in.

Best of luck, mate.

The plug wires on this model year and prone to burn through, replace them all, do one at a time and always put them back in the factory wire looms they run through, that is very important, replace any you may break. Use high qyuailty oplug wuires foractory parts are preferred..

Under load on take off from a stop or under heavy acceleration when already in motion could be one or more spark plug wires breaking down/misfiring.
You may be able to duplicate by opening hood, have someone set park brake and hold foot hard on regular brake pedal, block wheels also and press on gas pedal to simulate the loaded condition. Stand off to side, not in front of van and see if the engine misses and you may hear a snapping as the spark arc to ground. More common on the 3.3 engine.

What speed are you going when it chugs?
It could be as simple as a bad spark plug or a spark plug wire/boot grounding out.
When spark plug boots get old, the rubber cracks and lets voltage arc out the side and to the engine instead of through the plug.
This will be most noticeable when trying to maintain a speed of over 40 mph, or under mild acceleration.
The reason for being noticeable at this speed/acceleration level is that the transmission torque converter will be locked, transferring the vibration from any engine miss straight through to the wheels.

heh, you might want to change the title here as I am pretty sure you cant idle under heavy acceleration.
However I think you were on the right track with the plugs and wires. You didnt mention the cap though and that is usually the biggest culprit in damp weather. Put a new cap and rotor on it and see if that doesnt do the trick.

If you replaced the distributor cap then there is a high possibility that you put the wires in the wrong firing order on cap.

If all you did was replaced the plugs, then I would pull each one out and recheck the Gap sizes with a feeler gauge. Also check to see if the spark/coil plug wires are touching metal or each other, which can cause the spark to arc out of the wire and never get to the spark plug. If I suspect an arc and do not see a physical problem, I wait until nighttime and look under the hood while engine is running...they stick out like a sore thumb. Also make sure that you did not put the wrong plugwire to the wrong spark plug.

When you change your plugs, you should also replace wires, cap and rotor.

I am having the same problem with my mustang, have replaced tps, egr valve and sensor, clean maf, new plugs and wires, new fuel filter, cleaned throtle body and still having same problems....Please help!!!!!

Check engine light on? Most problem is spark plug wire breaking down. Replace spark plugs and wires.

Check the condition of the wiring coming off of the ECM. at the fender. I've seen the wiring insulation rub off causing no starts.