Why does my 2000 Yukon cut out while I"m driving?

check your fuses

You'll need to check the circuit from the fuel pump relay back to the pump. The computer grounds the relay.
If the pump is running the filter could be clogged.

I would venture the guess that your button is broken. The easy fix it to remove it and jimmy rig something manual to activate the function. Then everything will work fine. Additionally, be careful not to let your contraption rub against the actuator under the dash in that area because it could spark while you drive.

Had same issue, I replaced the MAF and this solved the issue, runs perfect now.

After time, the wires at the end of shifter break because they were cut short at factory and have little or no play. You will have to take column cover off where you can splice wire back together. It’s best to solder them together for best contact.

it sounds like the fuel pump might have died, or blew fuse or relay see if it gets fuel at the motor

It sounds like your fuel filter has got to the end of it's life and needs to be replaced. Once the fuel filter get's to dirty, the fuel pump can no longer keep the proper fuel pressure to the fuel injectors to have them work properly. The fuel filter should be replaced once a year or 30,000 miles to ensure that it's always clean. A dirty fuel filter will make the fuel pump work harder and shorten it's life time causing a costly fuel sending unit replacement. Good luck and be safe.

Chk MAF sensor (mass air flow) first sensor in ducting coming out of air filter.

* Use only one foot on the gas peddle - Just teasing. :)

My 2004 Yukon does same thing. Usually when I'm coming up to a stop. GMC dealer said "No fix."

I had the same problem with my 97 yukon. Replaced the Crankshaft Position Sensor on the front of the motor near the timing chain cover.