This sounds like you said it worked fine for about 50 miles, now you can't get it to turn over and start? Have You checked to see if fuel pump is working, or if You are getting gas to engine?
Practically the carb is fitted the way around that is most convenient for throttle and fuel connections, though theoretically it should be fitted the way around that produces the least mixture fluctuations due to fuel swill or surge in the float chamber during cornering and braking - I suggest you contact the manufacturer or a specialist for further information.
there will be a plug at the side top of the fuel bowl that you remove to check and adjust the float level while running
the float level is adjusted by the bolt at the top of the cover above the needle and seat adjust until the fuel is level with the threads of the plug
screw that mixture screw/s in all the way then back out 1 1/2 turns
start the engine and adjust the idle speed by the screw on the accelerator lever
set to around 800 rpms
adjust the mixture screw in until the rpms start to slow
now screw the mixture out until the rpms again slow
mixture adjustment is achieved by turning the screw back in 1/2 the turns that you used to turn it out from the slow in position to the slow position out
again adjust the engine rpms by the accelerator screw to the 800 rpms
most engines idle between 700 and 850 rpms unless and efi engine which have around 850 -950 rpms range
For those like me with a good old fashioned Holley type carb, here's a real nice video on the basics. He's gonna be doing more in-depth videos in the future. This cat flat out knows carbs!
I could go into all this and explain but its a simple fix adjustment and the par excellent video on U-tube shows you just how to do it. It is the same adjustment as a 650 edelbrock. So type in edelbrock 4 bbl carburetor adjustment and you will get there factory video. Its great shows you how to adjust the secondary on the choke side, you'll see. Hopes this helps Mike.