Sound goes out at random times, we have tried using speakers and it still does not work. It goes out for a couple days up to two weeks sometimes left it on for over 4 hours to see if it would come back on. Tried mutint and unmuting it to no avail. Help

Check the insert sockets.

Definitely need more info - such as type of amplifier or receiver, how many speakers you are running, whether the subwoofer is powered or not.
As a simple test procedure: Disconnect all speakers and plug in a pair of headphones. Get a strong audio signal? Good, move on. No signal or week signal, you have an amplifier issue before the audio even gets to the speakers.
Next: Disconnect all speakers, turn the volume down, and connect one speaker to the left output channel. Slowly increase the volume. If that works, do the same on the right channel. Everything OK? You're putting out enough gain on both channels. Sometimes one channel goes bad. You can still listen to your sound in mono moder, or drive two speakers from the single working output. Not stereo, but dual mono. Move on.
Connect left and right speakers but not the subwoofer. Repeat the test. Whatever is left is probably the problem. If the subwoofer is powered, check the power supply or incoming voltage. If the other speakers are driven off the subwoofer or powered from there, that's likely the problem.

there is a blower motor resister. it creates a lot of heat sometimes melting the electrical plug. check the plug for signs of melting and check the resister for deformation. Both parts can be purchased at rockauto.com

main power board bad.....

I would open it up (assuming it's a desktop pc not a laptop), and make sure the sound card (if it's an expansion card and not built-in to the motherboard), is properly seated (all the way in) in the expansion slot.

bad connection broken fratured wire just touching dirty or oxidized plug connection

It sounds like you're getting interference on the frequency you're using for your speakers. If there is any way to change the frequency, try that first.

there r some loose connection on the motherboard

Symptom: NO HOR SYNC
Cause: DEFECTIVE I008
Symptom: No Horizontal Sync. When PinP is called up, main picture may lock up for a 8 moment, then it goes back out of sync.
Cause: I008 defective (Sync Switch)

my speakers call creative on my computer wont work they use to,i hear sound but not audible