It is hard to predict compatibility of quarkexpress 6.1 with windows 10.
The best approach is to install it then see if it works and if it is not compatible windows 10 might show you prompt whether it is compatible or not. if it is, it will just work.
Do not forget to post the result for others to see.
This website has most drivers that you may need.
You can update your driver to work with windows Visa.
If not please let me know and I will get you what you need.
http://www.driveragent.com/ or click here
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