Can't block ads on macbook air

Try to figure out where the ad is coming from, most likely you have accidentally allowed a program to install on your computer. Go to the screen which allows you to check all the programs on your computer. Look down the list and see if there are programs which can relate to the ads you are seeing. My sister had a program which kept asking her to update drivers. I removed that program from the computer and no more ads popping up on the side of the screen.

remove apps which have ads content.

Install the free Ad-block Browser

• An alternative to your current browser is the free Ad-block Browser, made by the same company as the notorious AdBlock desktop extension.
  Block pop-up ads in ChromeIf it's really only the pop-up adverts that bother you and you'd rather not have to install a second browser then these can be blocked in Google's own Chrome browser. Launch the browser, tap on the three dots at the top right of the screen, then choose Settings, Site Settings.
  Scroll down to Pop-ups and ensure the slider is set to Blocked.
  Use Data Saver mode If you are sticking Chrome, there is another step you can take to avoid data-hogging content online.
  Data Saver compresses aspects of web pages that aren't required on mobile devices. It offers a smoother web browsing experience, and savings on your data bill as your phone no longer struggles to pull down unnecessary ads and animations.
  It can lead to a somewhat flatter browsing experience, and it is possible that some web pages will look wonky. But you can always disable Data Saver - it's a two-second job.
  Open up Chrome, and then hit the three dots menu icon in the top righthand corner. Choose Settings, then find Data Saver. Ensure this is set to On.
  

you bought the kindle with ads because it was cheaper,once you added it to amazon,it now will have ads forever

This page should help you out, it all depends on the browser you are using:

http://osxdaily.com/2011/05/10/ad-block-for-chrome-firefox-safari/

Hope this helps

You have to buy the no-add version.

You can reduce (or eliminate) the occurrence of pop-up ads by setting an Option in your browser that "Blocks Pop-Up" ...
If you're using IE Explorer, click on "Tools" (top right corner of screen - tool bar), put your cursor on "Pop-Up Blocker" (in the drop down window) and click on "Pop-Up Blocker Setting". Then, at the bottom of the window, set the "Blocking Level" at HIGH - which blocks all pop-up from showing up on your screen.

You can do it for other browsers as well ... e.g. Mozilla Firefox ...
click on Open Menu (the 3 horizontal bar on top right corner), select Options (in the drop down window), select the "Content" tab ... and check of the box (on the top) that says Block Pop-Up's, and then close.

Often pop-up's show up because your activity (viewing, searching, etc.) on the browser is tracked. Yes you can turn off tracking too !
This tracking info is used by "ads spawning" processes/apps to select which ads is displayed on your computer. So, you can reduce the amount of ad's by deleting cookies (particularly for these ads programs) every time you're done and close your browser ... just like you remove your (browsing) history, temporary files, cache information, etc.

In Safari, try selecting Safari >> Preferences from the menu and then click the Extensions tab. If there is an AdBlock extension listed there, try deselecting the Enable checkbox and see if things then start appearing properly again.

If they do, then you will need to figure out how to remove entries from your AdBlocking extension.

Is this where you are trying to disable pop up?? did you check on excetions button if site is added?