Pilot light will not come "ON" when trying to re-start (per instruction on water heater unit model # 22V50F1 ?

My first suspect is the thermocouple has failed (they should be changed periodically, every 5-7 years as they do fail). Without the signal from the thermocouple, the gas valve can not open and start the ignition process.

1) Copy following link to identify gas control valve:
http://waterheatertimer.org/How-to-troubleshoot-gas-water-heater.html#intellivent

2) Add a comment and describe gas control valve, and include if this is on boiler or water heater

If you need further help, I’m available over the phone at https://www.6ya.com/expert/gene_9f0ef4df2f9897e7

look at label on side of unit, then add a comment with Brand and type of gas water heater.
AO Smith tank-type, or Rheem tankless so expert can suggest best solution.

Tank-type:
Gas control could be bad.
http://waterheatertimer.org/pdf/How-to-replace-water-heater-gas-valve.pdf
Water heater is in lockout because combustion chamber overheated and tripped FV system because air intake is clogged.
http://waterheatertimer.org/How-to-troubleshoot-gas-water-heater.html#intellivent

If you need further help, I’m available over the phone at https://www.6ya.com/expert/gene_9f0ef4df2f9897e7

There are many reasons why pilot light can go out, from bad thermocouple to low air supply to dirty combustion parts, clogged orifice, low gas pressure, etc.
Copy following link and read information available for troubleshooting pilot outage.
http://waterheatertimer.org/How-to-troubleshoot-gas-water-heater.html#pilot

If you need further help, I’m available over the phone at https://www.6ya.com/expert/gene_9f0ef4df2f9897e7

Not enough information is given. Add a comment for additional help.
Does water heater have instructions printed on side of heater?
Are you trying to light pilot light?
What happens when you try to light the water heater?

More information is needed to give accurate do-it-yourself help.
Have you changed the thermocouple?
http://waterheatertimer.org/pdf/How-to-replace-thermocouple.pdf
http://www.youtube.com/watch?v=v0aBPsNg6vo

Some model numbers do not have a standing pilot light.
What do the re-light instructions show on side of unit next to gas valve? What does your manual say?
What type of gas control valve does unit have. Is this electronic gas control valve?
Add a comment with information.

Open following links for READING about general pilot light problems across different types and models of water heater: do-it-yourselfer will find useful resources.
http://waterheatertimer.org/pdf/Pilot-light-will-not-stay-lit.pdf
http://waterheatertimer.org/pdf/Standing-pilot-light-maintenance.pdf
http://waterheatertimer.org/How-to-install-gas-water-heater.html#troubleshoot

If the pilot is not lighting, you may have a lot of air in the gas line. If the pilot light is not staying lit, you may have to change the thermocouple.

http://www.hometips.com/repair-fix/water-heater-pilot-light.html

Check out this link for information on the topic of your heater.

sounds as if youll need a new thermocouple

replace the thermo