I can't sew on my machine

make sure your foot peddle is fully pluged in. It's a foot pedal error code.
Try unpluging your foot pedal and start the machine if it works without the foot pedal have the foot pedal repaired or replaced.

An E1 message appears on the panel Brother

Brother CS 6000 E1 error message my presser foot is not up

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Make Model E1 error

possibly the presser foot is still in the "Up" position?

Brother Computer Codes

• E1: Make sure the presser foot is lowered before sewing.
  E2: You chose a stitch other than a buttonhole stitch or a bar tack stitch and you tried to sew with the buttonhole lever in the lowered position. Raise the buttonhole lever.
  E3: If you selected the buttonhole or tack bar stitch and start to sew with the buttonhole lever raised, you will get the E3 code. Lower the buttonhole lever.
  E4: You hit the reverse button while the bobbin winder shaft was moved over to the right. Move the bobbin winder shaft to the left.
  E5: On automatic sewing machines, the start/stop button was pressed while the foot controller was plugged in. Unplug the foot controller if you are using the automatic function.
  E6: This code tells you that the motor locked up because the thread is tangled. Untangle the thread, make sure the machine is threaded properly and that the proper tension is set before continuing.
  

http://www.sewingpartsonline.com/instruction-manual-brother-cs6000.aspx

http://www.sewingpartsonline.com/instruction-manual-brother-cs-6000-instant-download.aspx

here's 2 links for you to choose from

have you pulled the buttonhole lever down before starting the buttonhole

An "E1" message appears on the panel. Description: The foot controller was pressed (or the start/stop button was pressed if the foot controller is not connected) and the reverse/reinforcement stitch button was pressed while the presser foot is raised.

Lower the presser foot lever before continuing the operation.

Error code E1:Make sure the presser foot is lowered before sewing.

In order to get this error the foot controller has to be pressed (or the start/stop button was pressed if the foot controller is not connected), and the reverse/reinforcement stitch button needs to be pressed while the presser foot was raised.

The only solution offer by Brother is to lower the presser foot lever before continuing.

This seems a bit simplistic so assuming you tried that already
Check to make sure there is no tangled thread interfering with the take-up lever.

This seems to be a common problem and it may be related to a computer issue rather then a mechanical fault.

In this case you may need to have the machine serviced.
I hope something here helps. I will investigate more and if I discover anything else I will pass it on.

you may need to have the machine serviced.

With the foot pedal disconnected from the machine, push the button with the - and upward arrow. to stop sewing use the same button. It is the first button closest to the needle.