SOURCE: Scanner will not connect to computer
'Twain' only means 'Technology without an important name', as this is refering to your printer/scanner, i would suggest that you disconnect the printer and remove any driver from Add/Remove programmes. Re-install printer software/driver and re connect printer when prompted and if possible in a different usb port, if that's how it's connected. If the problem persists and the pc is unable to communicate with the printer the fault will lie with the hardware. Hope it's only a driver glitch.
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