New 12 cup Mr Coffee hour and minute buttons don't work

First clean and please try again
Fill the reservoir with water.
Place your mug underneath the machine.
Add the K-Cup.
Choose your serving size.
Press the brew button to begin brewing.
Enjoy your delicious cup of coffee! .

I have one. there is a setting on how many cup you want 4,6,8,10, or 12 cups

you need to set the time on the clock , for this unit to work correctly

add one cup of distilled vinegar and let set overnight. brew the next morning to descale

you have an internal wiring problem, take it back and get a new one....siever

The following instructions shuld have you in hot coffee in the am.

S E T T I N G T H E C L O C K A N D D E L A Y B R E W T I M E
On programmable models CGX20/CGX23 & CGTX84/CGTX85 only
To Set the Clock:
1. Plug the power cord into a standard electrical outlet. The clock will flash on the control panel to
indicate that the time has not been set yet.
2. Press and hold the HOUR and MINUTE buttons until you
reach the current time. The PM indicator will light on the left
of the display.
The clock is now set!
NOTE: Pressing any button before setting the clock will cause
the clock to start keeping time from 12:00 a.m. You must set
the clock if you want to use the Delay Brew feature.
To Set the Delay Brew Time:
After setting the clock, simply press and hold the SET DELAY
button (Figure 1), and set the brew time by pressing the HOUR
and MINUTE buttons. The PM indicator will light up on the
clock display.
The Delay Brew Time is now set!
NOTE: To activate the DELAY BREW cycle, see the “Brewing Coffee Later” section.
To check the programmed time, push the SET DELAY button. The display will show the time you have
programmed the coffee to brew.

http://www.mrcoffee.com/Manuals/MANUALS/CGX20_43_62164399.PDF

Mine just started to do the exact same thing. So I decided to clean it using the "Clean" program and just water. I put the brewer through the cleaning program 3 times - each time it would brew water from 12 cups to 8 cups, I'd tap the brewer on the countertop, it would brew from 8 cups to 4 cups, tap it again, and it would brew the remaining cups. So, I called the Mr. Coffee help line (800-672-6333). The most-likely problem is that the hose is no longer attached in the water reservoir. The help line suggested that I take it in to a service center. I live in Urbana, IL and the closest service center is in Oak Lawn, IL - 2 hours away from me!!
Here is my solution:
1) Buy another coffee brewer.
or
2) Smash your current Mr. Coffee brewer into a million pieces (this relieves stress) and go buy another coffee brewer (probably stay away from Mr. Coffee products).
Hope this helps.
Frustrated in Urbana

Try unplugging it for several minuets & see if it clears it..

Unplug the coffeemaker for 20 minutes or longer - not a second less - in order to fully reset it. Then, when you plug it back in, turn the function dial to Clock again. Press and hold the HR button for a few seconds, and then set the hours. It should work now unless it got zapped, as you said.

Good luck!

-Tha Mp3 Doctor

You can download the complete manual in English here:
MRX35 manual