I have good spark on all 4 cylinders but it won't start up, i already replace the fuel filter.

fuel filter or a fuel pump could also be plugs, wires, cap and rotor I would try fuel filter first then take a plug off a cylinder and hold it close to screw driver or something(dont hold unless have rubber to grip to please dont get shocked) if it doesnt spark your not getting spark and try plugs wires cap and rotor if it does spark then open gas lid have someone turn ignition switch on and listen if you here the fuel pump is still good if not replace it. It does sound like a fuel pump

Do you have a good spark at the plugs?

How about the fuel pump...are you getting the fuel to the cylinders? Is the fuel making it through the fuel line through the fuel filter? Drop a few drops in 1 cylinder, if it fires, you have a fuel problem. Does it turn over? If not check out the motor starter!

Faulty fuel pressure regulator.

If it cranks but won't start the starter is already working which you now know.
You would have to figure out if you are missing spark to the plugs or fuel to the injectors, or low compression to proceed.

Did you check the fuel pressure before all of this fuel pump replacement? If the fuel filter is old enough to be clogged up, it should have been changed long before replacing a fuel pump unit. Your fuel filter should be changed every 30,000 miles. However, it would have to be TOTALLY clogged up to keep the engine from starting. It would have been causing all kinds of drivability problems LONG before that could happen.

Then, has anybody bothered to check for spark when the engine will not start? Has anyone scanned the onboard computer? (which happens to be in full control of both the fuel system and the ignition system)

You just might be trying to repair the wrong system...

There is no way anyone online can accurately tell you why it will not run without checking the vehicle first....although many uneducated DIYers might GUESS for you...which seems to be just as good as you are already doing....

PROPER DIAGNOSIS REQUIRED!

If this is a sudden occurrence and nothing suspicious happened prior, you most likely lost either gas or spark to the engine. You need to check for both.

Do you hear the fuel pump in the gas tank buzz on for a couple of seconds when you turn the ignition key to ON? Unless the fuel pump turns on and puts gas under high pressure at the fuel injectors, the engine cylinders won't get gas to start. Correct fuel pressure is crucial to know if you have a fuel pump (or fuel filter) problem. If the pressure is correct, it is probably not a fuel problem but a spark problem, although there are less common instances where a fuel injector circuit may malfunction.

The ignition system not producing spark at the spark plugs is the other common problem of no starts. Buy a cheap spark tester at a parts store, plug it into one of your spark plug wires, then crank the engine over and watch for a strong blue spark. You might need a helper to do this. If you see a consistent spark, the ignition system is probably good, although you should probably check more than just one plug wire-sometimes one bad ignition coil in a coil pack will cause no starting. Good luck.

check your codes first as it can be a number of things.

COULD BE STOPPED UP FUEL FILTER.CHECK FUEL PRESSURE SHOULD BE 48 PSI. IF LOWER HONDA ADVISE TO REPLACE FUEL FILTER.YOU HAVE TO REMOVE FUEL PUMP THROUGH ACCESS PANEL FROM THE FLOOR.IF FUEL PRESSURE OKAY.REPLACE AIR FILTER.REPLACE SPARK PLUGS IF YOU HAVE OVER 110000 MILES ON THEM.IF SPARK PLUGS BEEN CHANGED ALREADY.IF ENGINE STILL WONT CRANK AND IDLE.CODE SCAN FOR A FAULTY IDLE AIR CONTROL VALVE.

misfire can also be cause by stop up fuel filter or clogged fuel injectors or weak fuel pump pressure.