Front driver door actuator does not work - 2003 Lexus IS 300

DR/LCK fuse 25 amp . located in the I/P block
Fuse Block - I/P
In the right front kick panel

Power Door Locks System Components
The power lock system consists of the following components:
• Body control module (BCM)
• Driver door lock cylinder switch
• Front passenger door lock cylinder switch
• Driver door lock switch
• Front passenger door lock switch
• Door lock actuators in each of the doors
• DR LK Fuse 20-amp
Door Lock System Controls
The Power Door Lock System is controlled by the body control module (BCM) and can be activated by any one of the following:
• A door lock switch lock or unlock actuation
• A door lock cylinder switch unlock actuation
• A keyless entry transmitter actuation
• An automatic door lock actuation (Personalization function)
• An automatic door unlock actuation (Personalization function)
Door Lock Operation
When the body control module (BCM) detects a transition of either of the door lock switches to the lock position, it switches the door lock actuator lock control circuit to voltage. Since the lock actuator unlock control circuits are at ground potential within the BCM, the door lock actuator motors transition to the lock position.
Driver Door Unlock Operation
When the body control module (BCM) detects a transition of either of the door lock switches to the unlock position, it switches the driver door lock actuator unlock control circuit to voltage. Since the door lock actuator lock control circuit is at ground potential within the BCM, the left front (LF) door lock actuator motor transitions to the Unlock position.
The driver door lock actuator unlock control circuit is a dedicated control circuit used only for the driver door lock actuator motor. This is done so that the driver door may be unlocked by itself using a keyless entry transmitter or an automatic door unlock function (if programmed).
Passenger Door Unlock Operation
When the body control module (BCM) detects a transition of either of the door lock switches to the unlock position, it switches the door lock actuator unlock control circuits to voltage. Since the door lock actuator lock control circuit is at ground potential within the BCM, the passenger door lock actuator motors transition to the unlock position.
The door lock actuator unlock control circuits are dedicated control circuits used only for the passenger door lock actuator motors. This is done so that the driver door may be unlocked separate from the passenger doors using a keyless entry transmitter or an automatic door unlock function (if programmed).

Check for broke wires inside the boot from body to driver door , this is a common problem . If you don't find broke wire's , pull the door panel to get at driver door switch . Check for voltage an ground circuit .
Rendezvous Door Lock System Components
The power door lock system consists of the following components:
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Body control module (BCM)

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Driver door lock switch

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Front passenger door lock switch

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Door lock actuators in each of the doors

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Door lock system fuse into the BCM (BCM D 25A fuse)

Door Lock Operation
When the BCM detects a transition of either of the door lock switches to the LOCK position, it switches the door lock actuator lock control circuit to voltage. Since the lock actuator unlock control circuits are at ground potential within the BCM, the door lock actuator motors transition to the Lock position.
Driver Door Unlock Operation
When the BCM detects a transition of either of the door lock switches to the UNLOCK position, it switches the driver door lock actuator unlock control circuit to voltage. Since the door lock actuator lock control circuit is at ground potential within the BCM, the LF door lock actuator motor transitions to the Unlock position.
The driver door lock actuator unlock control circuit is a dedicated control circuit used only for the driver door lock actuator motor. This is done so that the driver door may be unlocked by itself using a keyless entry transmitter or an automatic door unlock function (if programmed).
Passenger Door Unlock Operation
When the BCM detects a transition of either of the door lock switches to the UNLOCK position, it switches the door lock actuator unlock control circuits to voltage. Since the door lock actuator lock control circuit is at ground potential within the BCM, the passenger door lock actuator motors transition to the Unlock position.
The door lock actuator unlock control circuits are dedicated control circuits used only for the passenger door lock actuator motors. This is done so that the driver door may be unlocked seperate from the passenger doors using a keyless entry transmitter or an automatic door unlock function (if programmed). This video on testing computer controlled door locks on a Subaru , doesn't matter . test yours same way > The BCM controls your door locks .
Are all of the power door locks inoperative from both door lock switches?

Power Door Lock Operation
The vehicle is equipped with power door locks. Each lock actuator is powered and controlled by the door module mounted in the individual door, but the rear integration module (RIM), which is the master control for the door lock system, determines when the lock functions are permitted. The RIM receives and examines the requested lock function from the individual door modules, or from the remote function actuator (RFA) via the class 2 serial data circuit. The RIM also examines the transmission shift selector position and the ignition switch position information available over the Class 2 serial data circuits. If the RIM determines that a lock or unlock function is permitted, it sends a class 2 message back to the individual door modules commanding them to perform that Lock or Unlock function.
Power Door Lock Components
The power door lock system consists of the following components:
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Driver door lock switch

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Passenger front door lock switch

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LH rear door lock switch

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RH rear door lock switch

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LH middle door lock switch (w/ V4U)

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RH middle door lock switch (w/ V4U)

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Driver door switch assembly (DDSA)

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Driver door module (DDM)

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Passenger front door module (PDM)

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LH rear door module (LRDM)

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RH rear door module (RRDM)

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Left middle door module (LMDM) (w/ V4U)

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Right middle door module (RMDM) (w/ V4U)

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Driver door lock actuator

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Passenger front door lock actuator

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LH rear door lock actuator

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RH rear door lock actuator

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LH middle door lock actuator (w/V4U)

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RH middle door lock actuator (w/ V4U)

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Driver door cylinder unlock switch

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Rear integration module (RIM)

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DRVMDL fuse (10-amp)

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PASS MDL fuse (10-amp)

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RRDR MDL fuse (10-amp)

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Class 2 serial data link

Do the power windows work ? DDM - driver door module fuse 15 amp - location is the instrument panel fuse box , plus LT DR circuit breaker 25 amp. Circuit breakers rarely go bad . The power locks are controlled by electronic's .The passenger side has another power supply ,that's why they still work .
Door Lock System Components
The power door lock system consists of the following components:
• The driver door switch (DDS)
• The passenger door switch (PDS)
• The body control module (BCM)
• The driver information center (DIC)
• The rear door lock/unlock relay (LBEC)
• The reversible door lock actuators in each of the doors and liftgate

The front power door lock switches are integral components of the driver door module (DDS) and passenger door module (PDS). The switches are 2 position normally open rocker switches. When placed in either the lock or unlock positions, the switches provide a direct input to the DDS or PDS. The DDS or PDS monitors these inputs and sends a LAN message indicating a change in the switch's respective position. Modules which activate the power door lock motors receive the LAN message and activate the motor in the appropriate direction to lock or unlock the vehicle's doors and liftgate. The rear door lock switch provides a lock and unlock signal to the body control module (BCM). The BCM upon receipt of a lock or unlock signal will control the rear door lock/unlock relay and also send a LAN message to the DDS and PDS to perform the appropriate function.
The modules which activate the power lock motors are:
• The DDS (driver door lock actuator)
• The PDS (passenger front door lock actuator)
• The BCM (both rear door lock actuators and cargo door/liftgate)
The DDS and PDS are directly connected to the respective door lock actuator through the door lock motor lock and unlock circuits. Once a door lock or unlock request has been received, the module will supply battery voltage to one side of the actuator and ground the other causing the doors to lock or unlock.
The rear passenger and endgate doors are controlled by the BCM through the rear door lock/unlock relay which is incorporated onto the printed circuit board in the LH BEC. The BCM controls the unlock relay by providing ground to energize the coil and controls the lock relay by providing battery voltage to energize the relay coil. The energized the relay and allows voltage to be applied to either the door lock motor lock or unlock circuits. Since the other side of the door lock actuator is connected to the normally closed contacts of the opposing relay to ground, the doors lock or unlock.

It's possible you have broken wire or wires inside the flex boot from the body of the vehicle to the driver's door . This happens a lot .
Fuse Block - I/P instrument panel
Left of the I/P behind the side trim panel

yes each door has an actuator. my guess would lead more towards the wiring than the actuator though. you will ave some time testing to see where the power ends and go from there.

Replace the driver side door actuator.

If you need further help, I’m available over the phone at https://www.6ya.com/expert/flavio_517b938f50183b92

door lock actuator might be faulty or bad electrical contact
take off the door panel and diconnect and reconnect the wiring, you might need to change door lock actuator

possible bad actuator ,wiring/connection problem,switch,actuator rod disconnected[clip popped off or broke-u can test power to switch but for the others need to remove door panel to access the lock system

yes the actuator is specific to each door. You can replace it yourself. Just be easy when pulling things off as not to crack plastics . Both of my 03 Accord actuators are out as well.

These directions might sound a little goofy. I'm trying to orient your location with front and rear rather then left and right because it depends on which door you are working on. Front is towards front of rig and rear, oh I think you get it.
1. Close window on door. 2. Using a flat screw driver pop off trim under inside door handle. I think there is a groove in the plastic to which the screw driver can be inserted. Remove screw. 3. Using same screw driver pop off trim panel with door lock and window control switches. Start lifting from end located at panel closest to the front of the rig. The panel towards the back end has a pivot point which holds the back of the panel into the arm rest. Dis-connect the two switches from the trim panel. 4. Again, using flat screw driver, pop off the trim pannel located at the upper door/window frame nearest the back of the rig. Remove screw. 5. Lift up the door panel to remove. Be careful the light bulb is attached to the door panel. Rotate light socket 90 degrees and remove. 6. From the rear of the door pull back the platic stick-on barrier. Don't remove the whole thing just pull it leaving about half of it towards the front of the door stuck on. 7. Remove the one 11mm bolt, located towards the bottom of door, which holds the rearwindow guide. Don't remove the two 11mm bolts which hold the horizontal brace. Nothing else needs to be removed, leave all rods and attachments in place. They all attach the the door latch and are not of any further concern.
8. Now the easy part. The actuators and door latches are separate components. The actuator slides onto the door latch via two metal guides located on the door latch. The actuator is held into place with a plastic locking tab. The locking tab is part of the actuator housing. 9. This tab has to be pushed in to release actuator from latch. 10. Find on ouside of door - rear where the latch fingers? (I don't know what else to call them) are located in the notched door frame. At the bottom of the notch is a very narrow opening, just a ****. This **** allows access to the locking tab on the actuator. 11. Orient the screw driver in the end of the **** closest to the interior. Working on a right door, looking at the locking fingers, facing the front of the rig, your screw driver would be inserted at the left side of the ****. Pushing a flat screw driver into the **** will push the locking tab allowing the actuator to slide off the door latch. 12. A flat screw driver or other small pry tool can be inserted between the actuator and the door lock to help slide the actuator off the metal guides. The pry unit can be inserted where the rod from the interior manual door lock stem is attached. Mine had a yellow snap/flip keeper. 13. The actuator slides off from the interior towards the outside door panel. 14. Simple put pressure onto the locking tab with one screw driver and gently pry with the other one and the actuator should slide right off.
15. I picked up an actuator at a u-pull it wrecking yard for five bucks and it worked fine. Dealer wanted $90.00 and auto parts wanted $127.00. When I pulled my actuator from the wrecked rig all door panels and interior where stripped. It took me literally 20 seconds to pull the actuator. 16. To install new unit slide actuator onto door latch rails and let locking tab click into place. You might have to manually move the interior door lock stem up and down until the finger on the actuator lines up with a hole on the plastic part of the interior lock stem.
16. I Want to thank TommyRox in Texas on Ford Truck World and rivguy on automotiveforums.com for their posts.