I wound the tailgate window up while the door was open. Now it wont go down and I cant close the door.

not really. it is best done with two people. remove the inside paneling, roll the window down and open the tailgate. then use a phillips screwdriver and push down the side tabs so the tailgate thinks it closed and roll the window up, have the second person hold the glass. You now have access to change the key cylinder.

it will not do both at same time and for some reason its not senson it is closed properly

This is a pretty common problem, Inspect the wiring in the tailgate jam area ,the wiring takes a lot of abuse ,every time the tailgate is open and closed the wiring inside the( black vinyl tube ) gets flexed back and forth and in time the wiring breaks some times if you open up the vinyl tube and inspect the wires it will appear the wires are ok but if you pull on the wire you'll find that it will actually stretch and all thats holding it together is the vinyl insulator ,also there are switches in the door latches of the rear gate that tell's if the tail gate is closed,if its not closed completely it will not allow the window to work properly hope this gets you in the right direction

This is how to replace it on a 1996 Blazer 4dr.

First, go buy the part you need at Rockauto. The link is for a 1996, but make sure you order it for your vehicle. Just do a search for a Window Actuator Rod Retainer. Rock Auto requires you order a pair of these, so make sure you order two. Each one has two of them in there so you will have 3 extras.
Window Actuator Rod Retainers - RockAuto.com

To open the window in the mean time while you are waiting for the part, do the following.
1. Remove the two screws on the door handle so you can pull back the door panel.
2. Pull back panel on top in the middle where it rises.
3. Reach in with a screw driver or your fingers to push down the lever. It's a metal piece on the left side against the wall to the inside of the blazer.
4. Open window and tailgate and remove screws on the sides of the tailgate. There is one on each side. Make sure it is the one fartest out and on the plastic panel.
5. Once the screws are removed, pull up on half the panel that is farthest out from the truck. Slide out away from the truck. The panel should come off with a little effort. Do not pull up on the panel closest to the truck, you will break the hooks that hold it in. I broke two on mine. The panel will slide away from the truck pretty easily.
6. Remove the screws holding the middle metal panel down. There are about 12 screws. They are the 9/32 socket screws.
7. Pull the metal panel up, first dislodge the metal poles connected to the two white clips on each side in the center of the panel.
8. You will now see your actuator with the broken blue clip.
9. Pop off the blue retainer from the actuator. This will take some effort but it will pop off. (here's where you can replace the actuator if it's not making a sound)
10. Place one end of the retainer into the loose metal piece that rotates (left arrow in third picture) and then pop the other end back on to the actuator.
11. Replace the metal panel and clip the poles back into the white clips.
12. Make sure your door handle rod is clipped into the lock before you close the tailgate. If not, you have to work at opening it again by sliding you arm down between the plastic panel and it's not easy.
13. Replace everything. Before you close the door, make sure the door handle works and make sure the actuator is connected.
14. You should now be able to use your tailgate window again!

I am taking a guess your trying to remove the tailgate panel to fix this problem???

Remove the interior trim panel which will not be easy since the gate is up ---- you can then access the lock mechanism and will probably find a bent linkage rod or a broken plastic retainer clip.

The electric key switch is next to the key cylinder on the rear door. You can see it easily with the window down and weatherstripping pulled out. The wiring may have become chaffed with the window over the years or the switch corroded in the contact points inside.

You will likely have to remove the panel from the inside with the window up. Once you have the panel off I would try to have some one hold down on the switch while you tap the motor with a hammer. Of course make sure the latches are all the way closed as if the door is not closed all the way the window will not roll down as it has safety switches to keep this from happening.

If you still can not get it down then you will need to unbolt the regulator and let it down that way.

if there are no broken wires inside the tailgate try lubing the latches with WD40 and open and close the tailgate several times. If the latches are properly closed on both sides the window will not work

The rear window has to be completely down in order to move the tailgate! You should be happy that your window is stuck up, unlike mine which is stuck all the way down! I have to completly take apart my tailgate!! If you want to try a trick to get the rear window down, my bronco has a rear window switch right next to the headlight knob, take the 2 purple wires on that window switch, and cross them, if your motor still works and if the wires are good, that should make the window go down!!! good luck, hope that helps!

my v70 vovlo estate(2000) tailgate wont open.checked fuses ok.no sound from mechansim when key fob depressed as the others do.Cant get into the back panel or open door at all.can you help with a suggestion?