Your question is alittle vague,...so Ill do my best...If your van has central locking (all the doors lock when you lock the drivers door with a key) then I can easily say that the actuator for the sliding door lock has malfunctioned....However if you are implying that you cant lock the sliding door from the outside using a key then it is because the linkage inside the door has came apart (Both issues would cause the door not to lock with the power lock button) If it is the linkage this is easily fixed by removing the interior panel on the slider and reconnecting the metal rod to its rightful place, if it is the actuator you have to replace it by removing the interior panel..Good luck
http://repairhelpcenter.blogspot.in/2012/02/front-door-dis-assembly-diagram-for.html
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http://repairhelpcenter.blogspot.in/2012/02/rear-door-dis-assembly-diagram-for.html
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This will help.
Thanks.
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