MY 2007 Lexus IS250 AWD suddenly when dead. I drive the car everyday without any problems. I drove it to work but when I got in it to leave work everthing was dead. I tied jumping it, nothing I then replaced the battery nothing it is still dead. It seems like a relay of some kind

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Use the key to unlock the drivers side door.

check solonoid for starter , battery wires , cable from switch to solenoid on starter ,

The first thing you want to check for is the brake signal,without this signal it will not crank,this is the easy one make sure you get brake light,the second is to have the starter tested by a direct method,this gives the indication of the health of the starter

Batteries currently last 3 years, have your battery tested and replaced

My wife has the Lexus IS250 with Navigation and just this morning she tells me she wanted to raise the AC from Low to higher position, but that nothing on the Navigation screen is working. I tried what David mentions above, but the only fuse that had 15A on it was in xlnt condition. Any other suggestions? Dealer talks like $1500 and the system has always been mediocre at best. Thanks for any help.

it has electric power steering, take it to the dealer and ask if the service campaign has been done on the power steering rack. if not then it will be free and they will wash your car for you, fill up your gas tank and replace the steering rack and align the car. if it has been done then maybe they didnt reset the steering gear ecu.

On North American IS250 it is to the right of the steering wheel below the ignition button. There should be two switches ECT and TRAC side by side

Try installing a K & N Air filter. Any good Parts store Carries them. Changed the HP and Milaeage on my 425 HP Chevrolet Truck. Added 35 to 45 HP and increased My Mileage to 23 Per Gallon!