I have a 2003 mazda 6 2.3 engine has a misfire. could this be an ecm problem?
Have the fuel trims been checked? These (short term fuel trim - STFT and long term fuel trim - LTFT) can be checked with an OBDII tool, and can provide a lot of information about what may be happening. If you have a vacuum leak, for instance, the O2 sensors will report a lean condition to the ECM and it will add fuel to the engine to try to correct. You will see this in the fuel trim numbers.
So, yes, the ECM can cause the misfire, BUT if so, it's because something is not right in the engine. Have a qualified technician evaluate ALL parameters and determine what may be wrong. You've spent a lot of money on parts (O2 sensors, coils, plugs, wires, PCV valve and hose, alternator), and have invested a lot of your time. It's very possible that none, or only a couple, of those parts needed to be replaced. Invest in the expertise of a trained technician.
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