On 10-26-17 I cranked my car and it ran fine, put the emergency break on . On 10/28 When I released the brake the VSA and brake light came on. Now when I crank it, I hear the blow fan coming on.

SOURCE: battary light on , engine cut off car won't crank

sounds like it's your alternator, your alternator charges your battery and runs car once it is started. if you have a bad alternator your battery light will come on, and shortly after your vehicle will die, unable to restart without a jump. I would take your battery to autozone or an auto shop to have your battery and alternator tested.

SOURCE: 2001 lexus ls430. Dead

Sounds as though when your battery died the engine imobiIiser locked down.
YOU MAY HAVE TO HAVE THE CAR TOWED TO A LEXUS DEALER AND HAVE THE MASTER KEY AND OTHERS REPROGRAMMED TO THE IGNITION...BUT
If you have your wallet key as well , try taking all to the airport. HOLD the card to the dash beside the ignition for at least 20 seconds, then try turning the key several times. I haven`t done an LS but the failsafe when a remote fails is to hold the key beside the ignition for at least 20 seconds ....
Also try the lock routine, but I think the issue is in dash..security needing to reboot to your key.
My understanding is that the lock routine re initialises the lock setstings when power is restored

SOURCE: emergency brake does not release

air filter could be cloged ,,and for your e brake theres a line in the back of your car underneath that sometimes gets stuck that would cause it

SOURCE: The car cranks fine (good battery) but will not

Hey all. I've had my 2003 in twice for the Crankshaft position sensor. In Feb 08 it fixed everything. My car wouldn't start when it had been running for a while. I'd pull into a gas station, then go to start it again and it would just turn over. Same thing just happened in July 2010. They replaced the crankshaft position sensor again, but now it's still doing the same thing. If I let the car sit for 20-25 minutes, it will start and run just fine. However, this time around the check engine light is on and it has never come on. I'm open to any suggestions as to what to try next. What is the PCM exactly?

SOURCE: My 2004 Lexus RX 330 has 105,000 miles and has

Sounds more like the Alternator or Voltage regulator is not charging the battery correctly. Have the Alternator checked. If you remove it and take it to Auto Zone or Advance Auto they should be able to test it for you.