2008 Lexus especially 350 rear window regulator install

Probably a blown fuse, this is how to replace it.
Interior Fuse Box Location 2007 2012 Lexus ES350 2008 Lexus ES350 3 5L V6

here is the fuse location
2007 Lexus ES 350 Owners Manual Page 325

It seems to me you may need to replace the low pressure sensor located inside the rim.

You need to take it apart the contacts need to be cleaned .
When the window is open water gets in their is corrotion
I do it to mine once every 2 years use denatered alc leaves no residue.

As long as there is power the windows should work. !st check fuses, then, if fuses are in tact check the switch itself.

from inside the trunk remove the trim/panel that encloses the lamp cluster then you can get to the clips/bolts that hold it in place

Replace your fuel filter and check the operation of your fuel pressure regulator. If there is a "CHECK ENGINE" light on or flashing, have it scanned for the failure code.

window relay

There is no asstton* on the 2008 ES350 to switch off the traction control (( pain in the *** when it snows+slippery )).

From forums online, and I\'ve personally tested/used this...

Keep the hand brake on (( its near the left leg )) when u switch on the car... And in the next few seconds, hit and release the brake twice, then
keeping your leg on the brake pedal, release the hand brake, and put it on again (( twice, your right leg on the brake all this while )), and then when the hand brake is on, hit and release the brake twice...

You will need to do this only immediately after the car starts, and it needs to be done in under 30 seconds (( from forums, never needed more than 10 seconds to do the whole thing ))..

They do not recommend it cause apparently, the torque generated can cause the wheels to spin so much that it causes tires to burn out soon... Good luck!

Try checking fuses, could be blown.

to reset, push odo buttom hold until put key on w/o start engine several seconds