I have a 03 Saturn Vue that has electrical issues sometimes it dose not start and I have to remove the ignition and main battery fuses to get it to start. Up cluster works when wants along with dash lights when key is in on positions everything works when in acc position.

Sounds like you mite need an ignition switch. But just to be sure you should have the modules scanned for codes , especially the body control module ! Are any warning lights staying on ,check ENG , A symbol of a wrench lit up or a picture of a lock symbol ? This car has a few electronic control modules and there all talk back an forth on a serial data bus . This car has two !
Class 2 Data Line
Saturn utilizes the class 2 communications system for most vehicle system controllers that must exchange data and commands. Class 2 data is pulse width modulated. The pulse width modulation of class 2 data allows better utilization of the data line.
The messages carried on class 2 data streams are also prioritized. This means if 2 devices try to communicate on the data line at the same time, only the higher priority message will continue. The device with the lower priority message must wait. The modules on the class 2 data line are:
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Body Control Module (BCM)

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Power Steering Control Module (PSCM)

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Instrument Panel Cluster (IPC)

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Inflatable Restraint Sensing and Diagnostic Module (SDM)

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Vehicle Communication Interface Module (VCIM), if equipped Controller Area Network (CAN)
The controller area network (CAN) serial data line is a high speed serial data bus used to communicate traction information between the electronic brake control module (EBCM), the engine control module (ECM), the body control module (BCM), and the transaxle control module (TCM). Typical data-transmission speeds must be high enough to ensure that the required real-time response is maintained.
The addressing scheme employed with CAN assigns a label to every message, with each message receiving a unique identifier. The identifier classifies the content of the message, such as engine speed.
Each module processes only those messages whose identifiers are stored in the module's acceptance list. This is CAN's form of message filtering.
The identifier labels both the data content and the priority of the message being sent. Each module can begin transmitting its most important data as soon as the bus is unoccupied. When more than one module starts to transmit simultaneously, the message with the highest priority is assigned first access. A module responds to failure to gain access by automatically switching to receive mode. The module then repeats the transmission attempt as soon as the bus is free again.
You need to have a professional scan tool to check for codes in the modules other than the engine ecm module. I have seen a bad instrument cluster short the bus and cause the vehicle shut down . hope this helps ! First place to start is checking for codes in all the modules. If there is a problem with one of them ,it usually sets a code in one of the other modules !