What causes 1995 isuzu vapor lock problems?

When it dies check for spark at a plug wire , stick a screw driver in the end of the plug wire an hold near ground (metal on the engine ) Doesn't always have to be a fuel problem . Ignition modules can cause this also. Transistors in the module could be shorting out when hot . Rather then guessing as to what the problem is , test ! Fuel pressure test's too ! Do the cooling fans work , engine hot fuel vaporizing in the fuel rail . Check engine light on ?

no
more likely a hydraulic lock from excessive fuel on a piston cause by leaking injector /seal
remove the plugs and see if the engine will then turn over after it sprays the fuel out of the problem cylinder
vapor locks occur in fuel lines where the fuel boils off filling the line with air and locks the fuel by not allowing flow in the line

Vapor lock can be caused by many different things, all coming down to the same root cause: too much heat in the fuel feed lines.

Low fuel pressure can cause the amount of heat needed to vapor lock to be lower than normal, so checking fuel pressure is important. Fuel pump going out feels a lot like vapor lock.

Engine overheat can also cause vapor lock. Clogged fuel filter can cause vapor lock. The fuel line should be routed away from the exhaust system.

If it is a gas engine, its almost impossible to get vapor lock.
Vapor lock is when liquid gasoline turns to a vapor which will not flow thru a carburetor. The usual cause was hot fuel lines going to the carb.
Since the early 1980s engines have used fuel injection which uses liquid fuel under pressure.

Vapor lock occurs when the gas in a fuel line turns from liquid to vapor, before it reaches the engine. The first signs of vapor lock are normally when your engine begins to run roughly. The engine may sputter and hesitate. It will then stall completely and refuse to restart. It may seem like the car is out of gas or the fuel pump has failed. While these are possibilities, vapor lock may be the problem.

A vapour lock will not stop and engine from turning over but a hydraulic lock will . The difference is vapour compresses , fuel doesn't. Remove the spark plugs and wind the engine over to clear fuel that has leaked into the combustion chambers .

No.
To begin with, there is no such thing as vapor lock in the cooling system. Vapor lock is when liquid gasoline vaporizes due to excessive heat. If the engine got hot enough to turn coolant into vapor the engine would seize up.
Do you have trouble code numbers ?

Your engine is vapor locking.Somewhere in the fuel system the fuel is boiling causing vapor lock.Look at the fuel line where it is closest to a heat source like the intake manifold or exhuast system somewhere.You will need to insulate the line where ever it is close to or touching a heat source.

It could be a vapor lock issue. Vapor lock is typical in older vehicles. With the invention of fuel injection vapor lock has been minimized. What causes a vaporlock is underhood tempatures causing the fuel in the lines near the engine to evaporate causing a vaporlock. Now once the engine cools down, it will condense back into a liquid eliminating the problem. Fuel injection uses a lot more pressure than the old carburators did. One thing you can do is try replacing the three most important fuel system parts. The fuel filter, the fuel pump relay and the fuel pump. You need good steady pressure to push the vaporlock out of the lines. If one of these three parts is malfunctioning then it will allow the system to vaporlock. As for the gusage readings, taht could be just a bad sending unit.

I've owned a 96 Villager and a 97 Villager that both exhibited this problem on occaision. As I understand it the fuel pump is weak. When ambient temperature is high the gas line is subject to vapor lock. Usually my car gave a warning acting like it was running out of fuel in repeated fits. I had about 10 minutes to find a good place to pull off the road. That is why a 15-20 minute wait eliminates the problem. You can solve it by replacing the fuel pump with a higher rating. I personally chose not to spend the money and have put up with the few times a year the problem crops up.