How do i manually close the sunroof of my 2007 e320

HI
Usually - in the owner's manual - is info on closing it manually or try this: https://www.youtube.com/watch?v=NJRbVWor5Gg

1. Place the ignition switch in the ON position.
2. Push and hold the sunroof switch toward 2 . Once the sunroof has reached the full tilt position, release the switch. Push and hold the switch toward the 2 position again. After a delay of four seconds, the sunroof will make a small movement and backup.
3. Release the switch.
4. Within 5 seconds of releasing the switch, push and continuously hold the switch toward 2 . The sunroof will move from the tilt position to the open position and back to the close position.

might try spraying white lithium grease on the slides and open and close few times my g6 did the same thing grease it and open and closed a few times then it work

Try it both ways and check , but do not apply too much pressure

in the trunk on the drivers side there is a plastic bolt to turn, in your tool kit should be a socket thing that should fit it to turn it.

remove the sun roof motor drive and close the sunroof manually, then reinstall motor, which by the way is the most likely part to cause this.

clean out the channels!

The sunroof continues to open and close normally from front to back, but the vent stays open.

It sounds like it just needs to be reinitialized. Turn your key to the on position with motor off and hold the up/full vent button down for at least 30 seconds or until your sunroof either clicks or goes to the full vent position. That should fix your problem.

tilt the sunroof into vent position as far as possible then press and hold the same switch for 30 seconds until you see it move release the switch and immediately press and hold it again the sunroof will close and open fully then close again do not release the button until it reaches the closed position for the second time.

source: owners manual