Only running on two cylinders . have changed the pick up coil, cap rotor , ignition control module, spark plugs, wires

When troubleshooting an ignition "no-spark" issue, it's helpful to first understand how the system works in sequence. The process starts with the crankshaft position (CKP) sensor detecting engine rotation and cylinder position. The CKP signal is interpreted by the powertrain control module (PCM) which then sends a signal to the ignition control module (ICM). The ICM then drives the ignition coil which is when the high voltage (for spark) is created. From there, the high voltage goes through the ignition coil wire to the center of the distributor cap. Here, the spring-loaded button of the cap touches the center of the spinning rotor and transfers the voltage. The high voltage then jumps from the rotor to whichever pole the rotor is pointed towards at the outer edge of the cap; let's say it's cylinder #1. High voltage then travels through the cylinder #1 ignition wire to the cylinder #1 spark plug where it sparks and ignites the cylinder's air/fuel mixture. Considering these things, if there is no spark from any of the cylinder-specific ignition wires, the issue must be further upstream. Start by unplugging the ignition coil wire where it attaches to the distributor and check for spark; if present, the issue is with the distributor cap or rotor. If not present, the issue is further upstream. ICM and ignition coils are both pretty common failures, but further in-depth diagnosis would need to be performed in order to determine if there is a circuit failure, sensor failure, module failure, or other component failure. You can read more here: https://www.yourmechanic.com/article/how-to-replace-a-distributor-rotor-and-cap-by-tim-charlet

If cap and rotor are good, check there is a continuous symmetrical signal from the ignition pickup coil (inside distributor).

Have you ever heard of the "mechanics rule" that says if it ain't broke don't fix it? Put the old coil and module back in they're not part of a tuneup because they can last for the life of the vehicle or not lol. I hope this helps. Take Care.

Plug , coil or injector or in the pcm

Visit the on-line store, know as reliable-store, they have the repair manuals. I'm sure you will get the solution of your problem.
Best Manuals

probably a faulty ignition control module

1. The ignition system on your 5.0L uses a distributor type system and will include the following components:
   1. Ignition control module (ICM). Depending on the year of your specific Ford, it'll have a inner-fender mounted ignition control module or a distributor mounted ignition control module. hot sure which you have.
   2. Ignition coil. you replaced it.
   3. PIP (Profile Ignition Pickup) sensor. This is Ford's name for the crank sensor and is mounted inside the distributor. The most common name for this component is the pick up coil.
   4. Distributor cap and rotor. you replaced
   5. Spark plug wires. you replaced.
2. The thing to keep in mind about the ignition system is that all engine cylinders must get spark and the one thing that will stop the ignition system from creating spark on a wholesale scale is a BAD crank sensor.Have you pulled a plug then using some insulated pliers grounded it to the vehicle and turned it over to see if you have spark, that'll tell you alot.takes two people of course.Best of luck and hope this helps.

This diagram is for 1998-1995 Chevy 6 cylinder 4.3L engines.
Your got the firing order exactly correct, at 1-6-5-4-3-2, but here's the thing to double-check:
The distributor rotation is clockwise (note badly rendered arrow in picture).





Since you probably got everything right, then you're left with really unusual/rare causes of
failure of the ignition system:
(a) rotor button misaligned/failing to make contact?
(b) rotor button not pressed onto distributor shaft far enough therefore failing to provide correct
proximity to distributor cap contacts when coil fires
(c) coil wire or contact loose/disconnected - press coil wire firmly down into distributor cap.
(d) distributor shaft of other damage caused during installation of rotor.
(e) spark plug wires defective from factory
(f) spark plugs defective from factory
(g) battery low - may need a charge to start
(h) ICM (ignition control module) failure - hook up your HEI (high energy ignition) tester, and
watch the quality of the spark on each cylinder.
(i) fuel problem? If spark is being properly delivered, its gotta be a fuel problem...
(j) distributor cap not screwed down flush to top of distributor? maybe just on one side?

Inspect the inside of the distributor cap - if there are lots of little metal bits all over the inside
of the distributor cap, then you know you have a misalignment of some type in there, and the
rotor and cap are destroying each other. normal operation will throw a quota of spark-ed off
metal bits inside the distributor cap, but since your cap is brand new, your attempts to start
the engine should have rotated the distributor so few times, you should see no metal debris.

Inspect the distributor cap contacts to see if any spark marks are more of less in the middle
of the cap's proper "contact zone". If not, you've diagnosed an internal misalignment, which
you know how to correct.

How about the MAP SENSOR? Do you check it out?

I had the same problem with my 85 cj7 this week, I relpaced the ignition control module, plugs, wires, cap, rotor and the the coil; still had no fire to plugs. the problem turned out to be my distributor, replaced it today and she fired right up. Most likely it was the pick up module in the distributor that went bad.