1997 gmc sierra 3500 won't start

Check for fuel by pouring small amount of clean gas down throttle body and crank engine over. if it starts and runs just for a few seconds you have a fuel delivery problem

What have you checked so far ?
Is the coil getting power and a ground signal ?

COuld be some problem with the starter, sometimes, when the starter warm, occurs this no start condition.

spark plug wires or coil pack

Yes, the system is called Passlock, and malfunctions regularly. Go to this link for an explanation of how it works, plus some tricks and tips on how to reset it, or bypass it.

http://vatspasslockpasskeysecurityhelp.yolasite.com/

It sure could be. But, first...by "won't turn over" you do mean it cranks at normal speed but won't start?
A simple test of the fuel pump is to stand by tank and listen as someone turns key to on. When first turned to on, your pump will activate for 2 or 3 seconds, pressurizing the fuel system, and then shut off if the engine computer doesn't get a cranking signal. Do you hear it come on? If not, then something's not turning your pump on. If you can hear it buzz on briefly, then maybe it's your filter. Another test: Spray a little starting fluid into your intake manifold (remove the big hose going into intake manifold) while someone tries starting it.If it doesn't fire and try to stay running, then it's probably an ignition problem. But if it does fire off, then you know it's a fuel problem-likely your pump or filter. good luck.

If you are at or near the 100,000 mile mark then your fuel pump may have failed. If you remove the fuel filler cap and listen carefully at the filler neck while someone turns the ignition key to "run" [don't actually crank the engine] you should be able to hear the fuel pump buzz for about a second and a half as the key is turned On. If you don't hear the pump buzz then odds are your pump is dead. Your pump may have actually failed making it appear as though you ran out of fuel. Not to uncommon. Hope this helps and good luck!

For the ECM 1 fuse to open you obviously have a short to ground , start with the injector disconnected and see if ECM 1 fuse still blows.If it does disconnect crank sensor, also inspect wires for the injectors or any rub through wires here is a diagram

The fuel filter may need to be replaced, but wont fix the problem you have. Its just a maintenance item that should be done every 15k miles anyhow. Check it over, check the large hose between the air filter and the engine make sure its secure. see if all hoses are ok, if you see/hear a vacuum leak. If all looks ok, time to have it checked by a shop.

check to make sure ur starter motor is earthed correctly, u can always remove the starter motor and test it using a portable battery charger, just be careful of the pinion